The MA18 block of Xinjiang oil field belongs to lowpermeability reservoir, whose pressure sensibility is medium to strong. Fracture is adopted to develop this block. The effect of fracture was simulated by diamondshaped inversed 9 point pattern using Eclipse. The threshold pressure gradient and the voltagesensitive effect were taken into consideration in this pattern. Considering the position diversity of edge well，corner well and central well in the field of seepage flow， the different length of fracture was simulated In this way, the optimum parameters of the fracture were obtained. Finally, the regression relation of the fracturing effect and the fracture parameters acquired by the simulation of FracproPT were got which could guide the construction of optimal project efficiently.